What are three risks of GMOs?

Could you please elaborate on the potential risks associated with genetically modified organisms (GMOs)? Specifically, I'm interested in understanding three primary concerns or hazards that are often raised regarding their usage. Could you provide insights into these risks, discussing their nature and potential impacts on the environment, human health, or agricultural practices? I'm keen to gain a comprehensive understanding of these potential drawbacks in order to make informed decisions about the use of GMOs.