What are the long term effects of nicotine pouches?

As a concerned individual with a vested interest in public health, I'm curious to understand the potential long-term implications of nicotine pouches. Could you elaborate on the potential risks they pose to users' health over an extended period? Are there any studies or research that indicates potential cardiovascular, respiratory, or neurological issues that may arise from regular use? Furthermore, I'm also interested in knowing if there are any long-term psychological effects, such as addiction or changes in mood, that are associated with nicotine pouches. Your insights would be invaluable in helping me make an informed decision regarding the use of these products.