Do I need to remove upo seeds?

Excuse me, could you please clarify something for me regarding the handling of upo seeds? I'm curious, do I absolutely need to remove them before proceeding with my current project or task? I've heard varying opinions on the matter and would appreciate your expert insight. Could you elaborate on the potential benefits or drawbacks of leaving them intact, as well as any specific scenarios where their removal might be crucial? Thank you for your time and consideration.